Scientific Program
*It is based on the local time of Seoul, Korea. (UTC/GMT +9:00) Updated as of September 8
* [KOR] = Sessions in Korean
Thursday, November 11
Keynote Lecture
Date & Time | 11/11(Thu) 08:10-08:40 | Place | Room A |
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Progress in targeting KRAS directly
Frank McCormick (UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA)
Educational Session: New insights for clinical trials in IO era
Date & Time | 11/11(Thu) 09:00-10:40 | Place | Room A |
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Immune approaches to cancer therapy: Building on lessons from checkpoint blockade
Jedd D. Wolchok (Memorial Sloan Kettering Cancer Center, New York, NY, USA)
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Next generation immunotherapy beyond anti-PD-1 and CTLA4
Myung-Ju Ahn (Sungkyunkwan University School of Medicine, Korea)
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Academic clinical trials of CAR T cell therapy for cancer
Marcela V. Maus (Harvard Medical School, Boston, MA, USA)
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Immunotherapy with chemotherapy or PARP inhibitors : A game changer?
Seock-Ah Im (Seoul National University College of Medicine, Korea)
Session 1: Proteogenomics
Date & Time | 11/11(Thu) 11:00-12:40 | Place | Room A |
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Proteomic characterization of the RAS secretome
Peter K. Jackson (Stanford University, Stanford, CA, USA)
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Mobilization of LINE-1 retrotransposons in colorectal epithelium
Young Seok Ju (Korea Advanced Institute of Science and Technology, Korea)
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Systematic elucidation and pharmacological targeting of non-oncogene dependencies in single cells
Andrea Califano (Columbia University, New York, NY, USA)
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Gastric cancer proteogenomics
Daehee Hwang (Seoul National University College of Natural Sciences, Korea)
KCA Symposium 1: Neoadjuvant Treatment and Conversion Surgery [KOR]
Date & Time | 11/11(Thu) 15:50-17:05 | Place | Room A |
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Current issues with neoadjuvant chemotherapy and surgery in breast cancer
Jeong Eon Lee (Sungkyunkwan University School of Medicine, Korea)
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Current issues in neoadjuvant therapy of lung cancer
Kwon Joong Na (Seoul National University Hospital, Korea)
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Surgery after neoadjuvant therapy for locally advanced or borderline resectable pancreatic cancer
Ki-byung Song (University of Ulsan College of Medicine, Korea)
KCA Symposium 2: AI in Cancer Research [KOR]
Date & Time | 11/11(Thu) 15:50-17:05 | Place | Room B |
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Medical image analysis using deep learning
Sang Hyun Park (Daegu Gyeongbuk Institute of Science & Technology, Korea)
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AI application in cancer imaging
Joon Beom Seo (University of Ulsan College of Medicine, Korea)
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AI application in pathology
Seokhwi Kim (Ajou University School of Medicine, Korea)
Satellite Symposium 01 (ONO/BMS)
Date & Time | 11/11(Thu) 13:10-14:10 | Place | Room A |
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Transforming the treatment paradigm in GC/GEJ/EAC 1L: Nivolumab + Chemotherapy
Sook-ryun Park (University of Ulsan College of Medicine, Korea)
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Innovative treatment of aRCC 1L with superior long-term efficacy and tolerability: Nivolumab + Ipilimumab
Inkeun Park (Gachon University College of Medicine, Korea)
Satellite Symposium 02 (MSD)
Date & Time | 11/11(Thu) 13:10-13:30 | Place | Room B |
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Pembrolizumab+Lenvatinib: the promising combination treatment for advanced solid tumors
Min Hwan Kim (Yonsei University College of Medicine, Korea)
Satellite Symposium 03 (Illumina)
Date & Time | 11/11(Thu) 13:30-13:50 | Place | Room B |
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Enable Comprehensive Genomic Profiling from liquid biopsysolid tumors
Ja-Hyun Jang (Samsung Medical Center, Korea)
Satellite Symposium 04 (Bayer)
Date & Time | 11/11(Thu) 13:50-14:10 | Place | Room B |
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Larotrectinib – a new selective TRK inhibitor for NTRK fusion-positive cancer patients
Dae Ho Lee (University of Ulsan College of Medicine, Korea)
Proffered Papers Session
Friday, November 12
Waun Ki Hong Memorial Lecture
Date & Time | 11/12(Fri) 08:00-08:30 | Place | Room A |
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Tumor Microenvironment: Challenges and Opportunities
Gou Young Koh (Korea Advanced Institute of Science and Technology, Korea)
Session 2: Preclinical Models
Date & Time | 11/12(Fri) 08:50-10:30 | Place | Room A |
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Using a cancer dependency map
William C. Hahn (Dana-Farber Cancer Institute, Boston, MA, USA)
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Creation of tumor assembloids recapitulating epithelial-stromal interaction in human cancers: Role of Foxa1-Hedgehog-Bmp axis in tumor plasticity
Kunyoo Shin (Pohang University of Science and Technology, Korea)
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Organoid modeling of lung disease and lung cancer
Carla F. Kim (Boston Children’s Hospital, Boston, MA, USA)
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The cooperation of YAP and AP-1 in ductal cell-derived pancreatic cancer development
Dae-Sik Lim (Korea Advanced Institute of Science and Technology, Korea)
Session 3: Precision Medicine in Immuno-Oncology
Date & Time | 11/12(Fri) 08:50-10:30 | Place | Room B |
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Updates and advances in personalized cancer vaccines
Catherine J. Wu (Dana-Farber Cancer Institute, Boston, MA, USA)
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TCR-seq analysis in anti-PD-1-treated patients
Eui-Cheol Shin (Korea Advanced Institute of Science and Technology, Korea)
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Defining the actionable genome
David B. Solit (Memorial Sloan Kettering Cancer Center, New York, NY, USA)
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Updates in gastric cancer immunogenomics
Jeeyun Lee (Sungkyunkwan University School of Medicine, Korea)
Session 4: Targeting the RAS Pathway
Date & Time | 11/12(Fri) 10:50-12:30 | Place | Room A |
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Acquired resistance to KRAS G12C Inhibition
Andrew J. Aguirre (Dana-Farber Cancer Institute, Boston, MA, USA)
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Resistance mechanism and overcome strategy to RAF inhibitor belvarafenib
Tae Won Kim (University of Ulsan College of Medicine, Korea)
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Discovering and deploying chemical strategies to drug KRAS: The formerly undruggable oncogene
Kevan Shokat (University of California San Francisco, San Francisco, CA, USA)
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Novel route to control KRAS-driven cancers
Sunghoon Kim (Yonsei University College of Pharmacy, Korea)
Session 5: Novel Discoveries in Drug Screening
Date & Time | 11/12(Fri) 10:50-12:30 | Place | Room B |
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The discovery of context specific paralog dependence in cancer through combinatorial CRISPR screens
William R. Sellers (Broad Institute of MIT and Harvard, Cambridge, MA, USA)
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Harnessing tumor bioenergetics in de novo target discovery for refractory SEM subtype cancer : a new concept proposition
Jae-Ho Cheong (Yonsei University College of Medicine, Korea)
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Accelerating inhibitor discovery to functionally annotate deubiquitinating enzymes
Sara J. Buhrlage (Dana-Farber Cancer Institute, Boston, MA, USA)
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Microfabricated assays to investigate tumor microenvironment
Seok Chung (Korea University, Korea)
KCA Symposium 3: Practical Issues in AYA Oncology [KOR]
Date & Time | 11/12(Fri) 14:30-15:30 | Place | Room A |
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NCCN clinical practice guideline of adolescent and young adult oncology
Yeon-Jung Lim (Chungnam National University College of Medicine, Korea)
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Extracranial germ cell tumors in adolescents and young adults
Seung Min Hahn (Yonsei University College of Medicine, Korea)
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Adenocarcinoma in adolescents and young adults
Hee-Beom Yang (Seoul National University Bundang Hospital, Korea)
KCA Symposium 4: Next-generation Targeted Therapy [KOR]
Date & Time | 11/12(Fri) 14:30-15:30 | Place | Room B |
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Recent advance in the development of novel, selective and potent FGFR inhibitors
Hee Jun Kim (Chung-Ang University College of Medicine, Korea)
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HER2-targeted therapies - a role beyond breast and gastric cancer
Miso Kim (Seoul National University College of Medicine, Korea)
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Inhibitors of MET and RET in non-small cell lung cancer (NSCLC)
Min Hee Hong (Yonsei University College of Medicine, Korea)
KCA Symposium 5: Precision Medicine Based on Molecular Tumor Board [KOR]
Date & Time | 11/12(Fri) 15:50-17:05 | Place | Room A |
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Experience of molecular tumor board in sponsor-initiated trial
Jeong-Eun Kim (University of Ulsan College of Medicine, Korea)
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Making molecular profiling guided therapy a reality for Korean patients: KOSMOS adventure
Jee Hyun Kim (Seoul National University College of Medicine, Korea)
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Nationwide precision medicine to accelerate targeted cancer therapies
Soohyeon Lee (Korea University College of Medicine, Korea)
KCA Symposium 6: Clinical Trials in Radiation Oncology [KOR]
Date & Time | 11/12(Fri) 15:50-17:05 | Place | Room B |
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RTOG 1119: Phase II randomized study of whole brain radiotherapy/stereotactic radiosurgery with concurrent lapatinib patients with brain metastases from HER2-positive breast cancer
- a collaborative study of NRG Oncology and KROGIn Ah Kim (Seoul National University College of Medicine, Korea)
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Result and lesson from KROG 08-06 trial
Yong Bae Kim (Yonsei University College of Medicine, Korea)
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Proton Beam Radiotherapy (PBT) vs Radiofrequency Ablation (RFA) treatment for recurrent hepatocellular carcinoma: A randomized controlled phase 3 non-inferiority APROH trial
Tae Hyun Kim (National Cancer Center, Korea)
Satellite Symposium 05 (Pfizer)
Date & Time | 11/12(Fri) 13:10-13:30 | Place | Room A |
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Optimizing clinical outcomes for Asian patients with EGFR mutation-positive NSCLC
Yun-Gyoo Lee (Kangbuk Samsung Hospital, Korea)
Satellite Symposium 06 (Lilly)
Date & Time | 11/12(Fri) 13:10-13:30 | Place | Room B |
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Optimizing treatment for HR+, HER2- metastatic breast cancer patients
Joo Hyuk Sohn (Yonsei University College of Medicine, Korea)
Satellite Symposium 07 (AstraZeneca)
Date & Time | 11/12(Fri) 13:30-13:50 | Place | Room A |
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Why PACIFIC regimen in UR St.III NSCLC treatment? – evidence from PACIFIC 5Y OS data
Hyun Ae Jung (Samsung Medical Center, Korea)
Satellite Symposium 08 (Roche)
Date & Time | 11/12(Fri) 13:30-13:50 | Place | Room B |
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Tumor agnostic therapies toward precision medicine era
Byoung Chul Cho (Yonsei University College of Medicine, Korea)
Satellite Symposium 09 (Yuhan)
Date & Time | 11/12(Fri) 13:50-14:10 | Place | Room A |
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Treatment for advanced EGFR T790M-positive NSCLC
Tae Min Kim (Seoul National University College of Medicine, Korea)
Satellite Symposium 10 (Servier)
Date & Time | 11/12(Fri) 13:50-14:10 | Place | Room B |
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New hope for metastatic pancreatic cancer with liposomal irinotecan
Jaekyung Cheon (CHA University School of Medicine, Korea)